Endocrine Abstracts

This study is designed to test the hypothesis that the gonadotrophinresponses to GnRH are heterogeneous and that, in pituitary/parapituitary lesion patients, the test is of no value as a diagnostic discriminator.We carried out a 5-year retrospective review of GnRH results from a cohort of 104 male (46) and female (premenopausal 49, post-menopausal 9) patients with pituitary/parapituitary lesions. Serum LH and FSH levels were measur...

Introduction: TSH secreting pituitary adenomas (TSHomas) are often large and locally invasive. Following trans-sphenoidal surgery (TSS) patients frequently require adjuvant treatment with either anti-thyroid medication or somatostatin analogue therapy.Objective: To evaluate the value of a single subcutaneous octreotide test dose in predicting the the response to long term treatment in 5 patients with TSHomas.Methods: Five consecutive patients presenting 2000-02 were ev...